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Chromatograph Mass Spectrometer Product List

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High-precision, rapid, and robust characterization of peptides and proteins.

High-precision, rapid, and robust characterization of peptides and proteins.

Comprehensive acquisition of molecular weight, aggregates, amino acid sequence information, etc., using light scattering detectors and LC-MS.

SEC-MALS, which combines size exclusion chromatography and multi-angle static light scattering, is commonly used for the analysis of polymers but is also suitable for molecular weight analysis of low molecular weight (LMW) peptides. Multi-angle light scattering (MALS) detectors such as DAWN and miniDAWN are very useful for online measurement of the molecular weight of peptides under 1,000 daltons. LC-MS allows for detailed characterization analysis, including amino acid sequences and post-translational modifications. By combining LC-MS with SEC-MALS, comprehensive data can be obtained, ranging from detailed analysis to the overall molecular weight and aggregates of peptides. By clicking "Submit," you agree that Waters may use and process the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

  • Light Scattering Photometer
  • High Performance Liquid Chromatograph
  • Mass Spectrometer
  • Chromatograph Mass Spectrometer

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High-precision analysis of the complex physicochemical properties of mRNA medicines.

High-precision analysis of the complex physicochemical properties of mRNA medicines.

High-precision evaluation of molecular weight, structure, and aggregation using light scattering detectors and LC-MS.

mRNA has been gaining attention as a modality in recent years, but evaluation methods have not yet been established, posing challenges in product development. SEC-MALS (Size Exclusion Chromatography with Multi-Angle Light Scattering detection) serves as a powerful tool for evaluating important biophysical characteristics. By utilizing SEC-MALS, it is possible to measure molecular weight, size, and three-dimensional structure with high precision, obtaining essential information for the development and optimization of mRNA therapeutics. Furthermore, when combined with LC-MS, it enables more comprehensive characterization and biophysical property analysis. The use of LC-MS for the separation and analysis of synthetic nucleic acids is effective, allowing for the simultaneous acquisition of a wide range of information, including purity, impurity content, and sequence confirmation. With the enhancement of dedicated analysis software, anyone can easily perform data analysis, regardless of their experience with LC-MS. By clicking [Submit], you are deemed to have consented to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

  • Light Scattering Photometer
  • High Performance Liquid Chromatograph
  • Mass Spectrometer
  • Chromatograph Mass Spectrometer

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Gas Chromatograph Mass Spectrometer Pursuing High Sensitivity and Stability

Gas Chromatograph Mass Spectrometer Pursuing High Sensitivity and Stability

Provides the necessary sensitivity and dynamic range for each analysis! A gas chromatograph mass spectrometer with a new detector. It generates high productivity.

Introducing the Clarus SQ 8 GC/MS (Gas Chromatograph Mass Spectrometer). With the adoption of the new "Clarifi" Detector, the Clarus SQ 8 GC/MS pursues further sensitivity and stability, providing the necessary sensitivity and dynamic range for each analysis, resulting in high throughput and productivity. Additionally, it features the new ion source, SMARTsource, which enhances maintenance by further pursuing plug-in capabilities. 【Features】 ◆ Adoption of the new "Clarifi" Detector, achieving high sensitivity and stability ◆ Adoption of a new ion source, improving maintenance with further pursuit of plug-in capabilities ◆ Expansion of analytical methods with the GC sampler TurboMatrix series and Swafer technology *For more details, please refer to the PDF document or feel free to contact us.

  • Other industrial robots
  • Other physicochemical equipment
  • Gas Generator
  • Chromatograph Mass Spectrometer

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[Case Study] Residual Pesticide Analysis in Baby Food Using High-Resolution GC-MS

[Case Study] Residual Pesticide Analysis in Baby Food Using High-Resolution GC-MS

Achieving high selectivity and high sensitivity for accurate quantitative analysis of pesticide residues in food.

The Thermo Scientific Orbitrap Exploris GC mass spectrometer demonstrates excellent performance in pesticide analysis in baby food. This system provides high selectivity and sensitivity with mass resolutions set at 30,000 and 60,000, accurately detecting low concentrations of pesticides from complex sample matrices. The QuEChERS method using citrate buffer was employed for sample preparation. This technical document presents the performance evaluation results of linearity, sensitivity, mass accuracy, and ion ratios for 18 types of pesticides in baby food extracts. All pesticides were detected and identified at the lowest standard concentration of 0.005 mg/kg, with mass accuracy showing high reliability within 1.5 ppm across all concentration levels. 【Features】 ■ Accurate mass measurement at high resolution ■ High selectivity and sensitivity even in complex sample matrices ■ Easy data acquisition and analysis using Thermo Scientific Chromeleon chromatography data system (CDS) software ■ Good linearity with a coefficient of determination of over 0.99 ■ Mass accuracy within 1.5 ppm across all concentration levels

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  • Food Testing/Analysis/Measuring Equipment
  • Analytical Equipment and Devices
  • others
  • Chromatograph Mass Spectrometer

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